Project MK-ULTRA was a secret mind-control program run by the CIA during the 50s and 60s. It was an outgrowth of Operation Paperclip at the end of WWII. In addition to rocketry and engineering experts, the US military had also picked up Nazi specialists in psychology, biology and  chemistry. The CIA put them to work figuring out ways to make all sort of fancy drugs and esoteric devices. Over the next 15 years, MK-ULTRA used the American populace as their own personal lab rats, testing LCD on Army soldiers to examine the panic response, radiation on pregnant women and federal inmates for various reasons, ultra-low frequencies intended to induce memory loss on Navy sailors, and so on. The full extent of the projects aren’t known, because when Congress became aware of MK-ULTRA’s activities, the CIA director had already ordered the destruction of all project files. All that is known about the project is known through interviews conducted after the fact.

One of the few known facts is the list of stated material objects that MK-ULTRA developed when it was thinking up its first round of projects:

1. Substances which will promote illogical thinking and impulsiveness to the point where the recipient would be discredited in public.
2. Substances which increase the efficiency of mentation and perception.
3. Materials which will prevent or counteract the intoxicating effect of alcohol.
4. Materials which will promote the intoxicating effect of alcohol.
5. Materials which will produce the signs and symptoms of recognized diseases in a reversible way so that they may be used for malingering, etc.
6. Materials which will render the induction of hypnosis easier or otherwise enhance its usefulness.
7. Substances which will enhance the ability of individuals to withstand privation, torture and coercion during interrogation and so-called “brain-washing”.
8. Materials and physical methods which will produce amnesia for events preceding and during their use.
9. Physical methods of producing shock and confusion over extended periods of time and capable of surreptitious use.
10. Substances which produce physical disablement such as paralysis of the legs, acute anemia, etc.
11. Substances which will produce “pure” euphoria with no subsequent let-down.
12. Substances which alter personality structure in such a way that the tendency of the recipient to become dependent upon another person is enhanced.
13. A material which will cause mental confusion of such a type that the individual under its influence will find it difficult to maintain a fabrication under questioning.
14. Substances which will lower the ambition and general working efficiency of men when administered in undetectable amounts.
15. Substances which promote weakness or distortion of the eyesight or hearing faculties, preferably without permanent effects.
16. A knockout pill which can surreptitiously be administered in drinks, food, cigarettes, as an aerosol, etc., which will be safe to use, provide a maximum of amnesia, and be suitable for use by agent types on an ad hoc basis.
17. A material which can be surreptitiously administered by the above routes and which in very small amounts will make it impossible for a man to perform any physical activity whatsoever.

Most of the supplementary material surrounding MK-ULTRA remains classified at a TOP SECRET level, and it is still believed that there are on-going research projects that stem from the MK